P2RX3 and neoplasm: In cervical DRGs (C3–C8), which innervated the tumor-bearing back skin, we did not see a significant reduction in the percentage of P2X3+ neurons after CTCL (Figure 2C) but observed significant increases in ATF3 colocalization with P2X3 on days 40 and 60 (P < 0.001, Figure 2, B and D).