SPON1 and neoplasm: Furthermore, we performed immunohistochemistry analysis (IHC) to examine the expression of TNXB and SPON1 in formalin‐fixed paraffin‐embedding (FFPE) primary tumor samples, and we found that there was overall stronger staining of TNXB and SPON1 in GAC tumor tissues from patients with LNM than from patients without LNM (Fig. 4E).