On the whole, patients without electrolyte abnormalities tended to be younger and had a higher proportion of male and first admission, lower prevalence of AMI, DM and CKD, increased level of SBP, DBP and serum albumin, decreased concentration of BNP or NT-pro BNP, as well as more frequency usage of angiotensin converting enzyme-1/angiotensin receptor blockers (ACEI/ARBs) or β-blockers than participants with electrolyte disturbances. This evidence concerns the gene NPPB and diabetes mellitus.