ACE2 and atherosclerosis: DIZE was found to reduce the severity of hyperoxic lungs injury by inhibiting the inflammatory response and oxidative stress, to attenuate the myocardial infarction, and to prevent atherosclerosis by increasing ACE2 mRNA expression (Kulemina and Ostrov, 2011; Qi et al., 2013; Shenoy et al., 2013; Haber et al., 2014; Qiu et al., 2014; Goru et al., 2017; Fang et al., 2019; Qaradakhi and Gadanec, 2020).