Importantly, three common vertigo risk genes showed proteome-wide significant signals in both discovery and replication stages, including MTERFD2 (PBanner = 0.045, PROSMAP = 0.031), MGST1 (PBanner = 0.014, PROSMAP = 0.018), and RAB3B (PBanner = 0.045, PROSMAP = 0.035) (Table 1). This evidence concerns the gene MTERF4 and Vertigo.