Compared to the DSS group, AX+CA administration increased the relative abundance of Flavonifractor, Coprobacillus, and Clostridium_XIVa, and decreased the populations of Robinsoniella and Lactobacillus.Gut-derived Flavonifractor species could be involved in degrading flavonoids; oral administration of F. plautii has been shown to promote recovery from acute colitis in mice via suppression of IL-17 (41), attenuation of inflammatory responses in obese adipose tissue (42), and suppression of Th2 immune responses (43). Here, IL17A is linked to colitis.