Interestingly, RIOK2 expression in malignant tissues was lower than that in healthy tissues, as was the case for lung squamous cell carcinoma (LUSC), kidney renal papillary cell carcinoma (KIRP), kidney chromophobe (KICH), uterine corpus endometrial carcinoma (UCEC), and thyroid carcinoma (THCA) (Figures 1A,B, Wilcoxon p-value < 0.05). The gene discussed is RIOK2; the disease is thyroid gland carcinoma.