Consistent with the above results, we also found a positive correlation between the expression of RIOK2 and metastasis in BRCA, COAD, rectum adenocarcinoma (READ), and DLBC tumor cell lines, but a negative correlation between these two factors in OV (Supplementary Figures S2B–E, p < 0.05). The gene discussed is RIOK2; the disease is rectum adenocarcinoma.