Downregulation of miR-122-5p in HCC patients as well as HCC-derived cell lines was demonstrated together with an inverse correlation with cyclin G1 expression (Gramantieri et al., 2007) and upregulation of miR-122-5p was shown to repress the epithelial to mesenchymal transition (EMT) through the WNT/β-cadherin signaling pathway via Snail 1/2 (Jin et al., 2017). Here, CCNG1 is linked to hepatocellular carcinoma.