There are also many genes of relevance to immune function and susceptibility for autoimmunity located on the X chromosome, including those encoding IL2-Rγ, IL13-Rα, CXCR3, CD40 ligand, TLR7 and TLR8, TIMP1 and Bruton’s tyrosine kinase (BTK). The gene discussed is TLR7; the disease is Autoimmunity.