Infection of rhesus macaques with CMV is very similar to humans (60, 61), but detailed analyses of its impact on the CD94/NKG2 receptors on the protein level was hampered due to lack of specific anti-rhesus CD94 and NKG2 antibodies and that anti-human NKG2A antibody clone Z199 does not discriminate between CD94/NKG2A and CD94/NKG2C of rhesus macaques (35, 36). This evidence concerns the gene KLRD1 and infection.