HCMV infection not only impacts the NK cell repertoire by clonal expansion of NKG2C+ NK cells, but results also in altered function of these cells as evidenced by low expression of IL12RB2, IL18RAP, ZBTB16, FCER1G, SYK and SH2D1B (9, 18). Here, KLRC2 is linked to cytomegalovirus infection.