Notedly, there was no difference in LIPT1/PDHA1 expression between MCF-10A and BT-549 cells, but their expression in receptor-positive breast cancer cells was higher than that of MCF-10A, which might indicate that the difference of LIPT1 and PDHA1 expression was related to the receptor status of BC (Figure 2). The gene discussed is PDHA1; the disease is breast carcinoma.