PDHA1 and breast cancer: Previous studies demonstrated that PDHA1 could regulate the growth of breast cancer cells by the coordination of glucose metabolism reprogramming (30).To further elucidate the role of PDHA1 expression in the clinical features of BC patients, we verified that PDHA1 expression was associated with T stage from the database and subsequently collected 30 breast cancer samples to confirm that PDHA1 expression was higher in T2 stage than in T1 stage (Figure S3).