EPCAM and experimental autoimmune encephalomyelitis: In previous work, despite reduced numbers of CD207+EPCAM+ migratory DCs detected in the DLNs of ACKR2-/- mice at day 3 post immunization with antigen, deficiency of ACKR2 did not impair T-cell priming and subsequent development of experimental autoimmune encephalomyelitis (30).