IL1B and Allergy: In order to investigate the potential role of genetic susceptibility in addition to allergy in these patients, we thus aimed to (i) perform the examinations by including symptom free arthroplasty patients, (ii) focus on the IL-1B-gene with the polymorphisms IL-1B-3954 (rs1143634), IL-1B-31(rs1143627), IL1B-511(rs16944) and one mini satellite polymorphism (IL-1RN Intron 2 VNTR, rs2234663) and (iii) further evaluate the results by including the atopy - background and test results of the patients.