They found that ALKBH5 may exert tumor-promoting effects in AML by post-transcriptional regulation of a critical target, TACC3, a prognosis-associated oncogene in various cancers.72 Therefore, these 2 studies clearly uncover the selective and important role of ALKBH5 in the pathogenesis of AML. This evidence concerns the gene ALKBH5 and acute myeloid leukemia.