Overall, PNN+ and PNN+/PV+ densities were significantlly decreased in the roCg1 (GLM, control mean ± SD = 40.55 ± 10.57/mm2 vs. MD mean ± SD = 32.47 ± 10.45/mm2, n = 5, p < 0.001 and control = 33.98 ± 12.68/mm2 vs. MD = 27.60 ± 11.44/mm2, n = 5, p < 0.001, respectively; Figures 2A,B) and IL (GLM, control = 35.57 ± 7.71/mm2 vs. MD = 27.62 ± 8.89/mm2, n = 5, p < 0.001 and control = 31.72 ± 8.81/mm2 vs. MD = 22.03 ± 9.46/mm2, n = 5, p < 0.001, respectively; Figures 2A,D) of young adult MD rats compared to controls, while no differences were found in the PrL (Figures 2A,C). The gene discussed is PNN; the disease is Menkes disease.