Mutations in the rdx gene encoding radixin (Rdx) (Figure 1A) cause non-syndromic hearing loss (DFNB24; OMIM #611022) in human patients (Khan et al., 2007; Shearer et al., 2009; Bai et al., 2019; Prasad et al., 2020). The gene discussed is RDX; the disease is hearing loss disorder.