According to our findings, LETZ- induced PCOS-mice showed significantly reduced (p < 0.001) levels of SOD and CAT in the ovary when compared to control mice, However, in the group administered with LETZ+GA,we observed significant increase(P < 0.001) in the SOD and CAT levels as compared to the LETZ-induced PCOS untreated group. This evidence concerns the gene CAT and polycystic ovary syndrome.