NDUFV3 and mitochondrial disease: The top 25 hits based on p-values displayed proteins that segregated with memory loss, amnesia, epilepsy, Schizophrenia, Parkinson’s, nervous system disorder, etc. Interestingly, the analysis also showed various mitochondrial diseases such as Leigh syndrome due to mitochondrial complex I-V deficiencies, alteration in NADH dehydrogenase [ubiquinone] flavoprotein 3 expression (NDUFV3), providing more reasons to investigate Pb2+ toxicity on mitochondrial physiology as stated earlier (Fig. 8, Supp.