CYP1B1 and primary congenital glaucoma: Despite these limitations, the study presented here to some extent overcomes them as it was a comprehensive in silico study where molecular dynamic simulation was also performed to enhance the reliability of the results, thereby providing a quick, critical, and cost-effective approach to evaluate the mutational spectra of the CYP1B1 gene and to discover the probable biomarkers that can be helpful for the understanding and management of primary congenital glaucoma.