Many studieshave recently reported that MUC4 and MMP7 are expressed differentially in biopsies of gingival tissue taken from periodontitis patients and healthy controls investigated through RNA sequencing [5-8].Therefore, it is of interest to evaluate the levels of Mucin 4 and matrix metallo-proteinases 7 in saliva and GCF samples [9,10] taken from periodontitis patients and healthy controlsin adolescents' patients at West Bengal, India. Here, MMP7 is linked to periodontitis.