The network generated from the significantly upregulated proteins revealed high level of connectivity among 3 proteins such as Lipoproteins a (LPA), C-reactive protein (CRP) and lipopolysaccharide-binding protein (LBP) (Figure 2A - see PDF).We identified significant over expression of LPA (Lipoprotein (a)) in the serum of psoriasis patients as compared to the serum from healthy individuals (Fold change +2.16, p=0.01). This evidence concerns the gene CRP and psoriasis.