Atrogin-1 is a E3 ubiquitin ligase induced in catabolic states (Bodine et al., 2001; Gomes et al., 2001; Cunha et al., 2012; Bodine and Baehr, 2014) and MyoD is a regulator of skeletal muscle differentiation downregulated in a pro-inflammatory environment such as cancer cachexia (Guttridge et al., 2000). This evidence concerns the gene FBXO32 and cancer.