Furthermore, the latest research found that a large number of immune checkpoint receptors (including PD-1, TIM-3, and CTLA-4) as well as lymphocytes infiltrating (such as B cells, T cells, macrophages, and dendritic cells) positively correlated with the level of m6A readers YTHDF1, and YTHDF2 in respective cancer type, including glioma, NSCLC, kidney renal clean cell carcinoma and BC [107–110]. The gene discussed is YTHDF1; the disease is non-small cell lung carcinoma.