A lot of effort has been made to define the most relevant screening strategies which could help to identify patients at increased risk of developing cardiomyopathy (Lipshultz et al. 2012), but there is still no consensus recommendation considered as the gold standard, Akat et al. (2014) showed that miRNA assessment outperforms the cTnI marker routinely used in heart disease. This evidence concerns the gene TNNI3 and cardiomyopathy.