GPI and disseminated peritoneal leiomyomatosis: However, glucose phosphate isomerase (Gpi; P < 0.0001) and mannose phosphate isomerase (Mpi; P < 0.05), responsible for catalysing G6-P and M6-P respectively to F6-P, were significantly reduced in LPD in RNA sequencing and confirmed by qRT-PCR (Fig. 3D).