We enumerated the proximal interactions of naive/memory (CD8+PD-1−TOX−), activated/predysfunctional (CD8+PD-1+TOX−) and dysfunctional (CD8+PD-1+TOX+) T cells with PD-L1-expressing cancer cells (pan-cytokeratin (panCK)+PD-L1+). Here, CD274 is linked to cancer.