In contingency tables, the distribution of HER2 positivity (Fisher’s exact P = 0.48, Fig. 2D), ER positivity (P = 0.66, Fig. 2E), PR positivity (P = 0.48, Fig. 2F) and Ki67 positivity (P = 0.63, Fig. 2G) was similar between primary tumour and metastases. This evidence concerns the gene MKI67 and neoplasm.