Similarly, when the GATA2 transcription factor regulatory t-values (rabit.dfci.harvard.edu)25 were compared in the TCGA breast cancer cohort, African American patients showed a significantly lower GATA2 t-values (Fig. S7c), indicating a more significant and prevalent impact of GATA2 as a negative transcription regulator in African American patients. This evidence concerns the gene GATA2 and breast cancer.