NOD2 and colorectal carcinoma: As with P. intermedia, Parvimonas micra (P. micra) was abundantly found in CRC patients’ fecal samples, suggesting its role in CRC.58Parvimonas micra has been shown to interrupt nucleotide-binding oligomerization domain 2 (NOD2) - an innate immune sensor - leading to the development of periodontitis.