LPL and type 2 diabetes mellitus: In view of this and the impact of lipid changes in modulating the fluidity in membranes and lipoproteins [78,[86], [87], [88], [89], [90]], the reduced bioavailability of (poly)phenol metabolites in T2DM may turn fluid triglyceride-rich VLDL even more fluid, and prevent the binding of VLDL to endothelial lipoprotein lipase (LPL) to release TAG [91] leading to the accumulation of circulating TG-rich particles in T2DM patients.