In the male SNO protein dataset, proteins were found to be involved in networks designated as “FCERI-mediated NF-κB activation network,” “Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer’s disease models,” and “WNT signaling” (Fig. 3A). The gene discussed is NFKB1; the disease is early-onset autosomal dominant Alzheimer disease.