A nanoparticle-based system, composed of the gallium(III)complexof a minimally substituted corrole that is coated by transferrin asa targeting vehicle (3-Ga NPs), has been used for pre-clinicalevaluation of its efficacy against human metastatic castration-resistantprostate cancer (mCRPC) tumor xenografts. The gene discussed is TF; the disease is neoplasm.