Approximately 80% of the positive associations of BMI and waist circumference with ischemic stroke were explained by a set of well-established cardiovascular risk factors (SBP, low-density lipoprotein cholesterol, triglycerides, and HbA1c), and associations were only minimally attenuated after further adjusting for C-reactive protein, estimated glomerular filtration rate, alanine transaminase, and uric acid (Figure 2). Here, GPT is linked to ischemic stroke.