After adjusting for age, sex, initial NIHSS, prior stroke, and AF, participants in the MSU were more likely to received reperfusion treatment (IV tPA and/or EVT) compared to the walk-in and EMS groups (odds ratio, 2.83; 95%CI, 2.01–3.99 for MSU vs walk-in and odds ratio, 2.18; 95% CI, 1.43–3.32 for MSU and EMS). The gene discussed is PLAT; the disease is atrial fibrillation.