In one (0.6 per cent) patient with persisting hypercalcaemia, the hyperfunctioning parathyroid gland could not be localized and a further one (0.6 per cent) patient was still hypocalcaemic following initial BNE with subtotal parathyroidectomy for MGD, thymectomy, and hemithyroidectomy for unilateral thyroid nodules with PTH in the low-normal range. This evidence concerns the gene PTH and Hypercalcemia.