Because of the current lack of awareness of CS complications, many subjects with CS have been misdiagnosed with hypertrophic cardiomyopathy or dilated cardiomyopathy, and as a result have been administered conventional therapies including angiotensin‐converting enzyme inhibitors or other vasodilatory agents, diuretics, β‐blockers, or sildenafil.9 This evidence concerns the gene ACE and hypertrophic cardiomyopathy.