AKT1 and type 2 diabetes mellitus: A single oral dosage of an acylated anthocyanin extractfrom purple carrot and an equivalent dose of two nonacylated anthocyanins(delphinidin-3-O-rutinoside and cyanidin-3-O-glycoside, 1 mg/kg body weight) have been used to assesstheir capacities to phosphorylate AKT phosphorylation in the aorta.54 As compared to the other two nonacylated anthocyanins,acylated anthocyanin extract has exhibited a higher level of AKT phosphorylation.54 This result suggests acylated anthocyanins mightplay a better role in regulating AKT phosphorylation in T2D (Figure 2).