As revealed in the KEGG findings (Figure 4), 20 top signaling pathways were characterized, including proteoglycans in cancer, pathways in cancer, prostate cancer, thyroid hormone signaling pathway, endometrial cancer, colorectal cancer, central carbon metabolism in cancer, pancreatic cancer, MAPK signaling pathway, HIF‐1 signaling pathway, hepatitis C, thyroid cancer, hepatitis B, bladder cancer, viral carcinogenesis, non‐small cell lung cancer, apoptosis, glioma, epithelial cell signaling in Helicobacter pylori infection, and melanoma. The gene discussed is HIF1A; the disease is melanoma.