The innate system has components such as Toll-like receptors (TLRs) that release interferons (IFNs), tumor necrosis factor (TNF), and interleukins (ILs), whereas the adaptive system flares up using the complement pathway and bone marrow and thymic type of lymphocytes, which plays a role in the pathophysiology of lupus [5]. Here, TNF is linked to systemic lupus erythematosus.