Posti et al. [23] found that Nf-L was capable of distinguishing isolated mTBI patients based on CT results (AUC: 0.662 (95% CI: 0.512-0.812), p = 0.049), with a higher median Nf-L level in CT-positive patients (14.0 pg/ml) compared to CT-negative patients (8.23 pg/ml). The gene discussed is NEFL; the disease is concussion.