PVMs,31, 82, 83 perivascular cells,23 CD14+/CD16+ peripheral blood‐derived monocytes84 participate in HIV/SIV encephalopathy, meanwhile, PVMs and meningeal macrophages (MM) also play vital roles during the early stages of experimental allergic encephalomyelitis (EAE) development.85 This evidence concerns the gene CD14 and Encephalopathy.