Furthermore, the one-way ANOVA analysis showed seven lncRNAs increased with tumor progression (NORAD p = 0.025, LINC01578 p = 0.023, AC004542.2 p = 0.025, ZFAS1 p = 1.17 × 10− 8, EBLN3P p = 0.002, THUMPD3-AS1 p = 0.044, GAS5 p = 2.26 × 10− 7), which implied the expression levels of these lncRNAs had a highly consistent variation tendency with the grades of PCa (Fig. 4). The gene discussed is ZFAS1; the disease is posterior cortical atrophy.