SCARA5 and esophageal squamous cell carcinoma: Since overexpression of SCARA5 increased the cell death of ESCC cells, the cytostatic were used to explored the reason affecting the proliferation activity of ESCC cells, and it was found that apoptosis inhibitors, autophagy inhibitors and necrosis inhibitors did not restore the decrease in cell activity caused by overexpression of SCARA5, while ferroptosis inhibitors restored cell viability and the ferroptosis inducer reduced the cell activity in overexpressed SCARA5 group.