This case showed scattered loci of [18F]RO948 binding but none  ≥ 1.65 on W-scores and with no pattern corresponding to the atrophy in that case, nor to bvFTD ALS atrophy in general nor to the distribution of TDP-43 type B inclusions in FTD-ALS cases, which is dominant in frontal, temporal, and motor cortex [28]. This evidence concerns the gene TARDBP and amyotrophic lateral sclerosis.