YTHDF1 and neoplasm: Many cancer cell lines and tumours globally overexpress modified RNA (Cui et al., 2017a; Zhang et al., 2017; Ma et al., 2019; Lin et al., 2016) and in Ythdf1−/− mice, tumour neoantigen cross-presentation is reduced resulting in impaired immune evasion (Han et al., 2019).