HLA-A and neoplasm: With respect to the class I (HLA-A*02:01)–restricted, HPV-16 E629-38 TCR obtained from HNSCC TILs, recognition was, perhaps unsurprisingly, affirmed for both an autologous tumor cell line and a well-characterized HLA-matched and E6-expressing tumor cell, CaSki (importantly, see Figure 2).