RAG1 and stroke disorder: Importantly, no difference in infarct volumes was observed between WT and Rag1−/– mice (Figure 3—figure supplement 1B) and in TH1 or TREG-supplemented Rag1–/– mice (Figure 3—figure supplement 1C), suggesting the transcriptional changes observed in microglia are primarily due to T cell subsets and not biased by differences in stroke severity.