ITGB1 and familial pancreatic carcinoma: MiR-760 and miR-199a-5p also downregulated ITGB1 indirectly, the former downregulating MOV10 mRNA, an RNA-binding protein that stabilizes ITGB1 mRNA (the miRNA acting as an anti-proliferative/pro-apoptotic TSG in pancreatic cancer) [85].