CD30 is not always universally expressed on all PTCL cells, but has a prevalence of around 32–64% in PTCL not otherwise specified (PTCL-NOS), 50–100% in enteropathy-associated T-cell lymphoma (EATL), and 46–80% in angioimmunoblastic T-cell lymphoma (AITL) [2]. The gene discussed is TNFRSF8; the disease is angioimmunoblastic T-cell lymphoma.