AGO1 and infection: However, E/V infection robustly potentiated the transcription of the RNAi pathway components, including Dcr-2 in the siRNA pathway, AGO3 in the piRNA pathway, and Drosha, Dcr-1, and AGO1 in the miRNA pathway, while E/C infection exerted little effect on the RNAi pathways (Fig. 4).